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2010 AHA/ASA 美國卒中或短暫性腦缺血發(fā)作患者卒中二級預防指南   內容預覽：

    The aim of this statement is to provide clinicians with the most up-to-date evidence-based recommendations for the prevention of ischemic stroke among survivors of ischemic stroke or TIA. A writing committee chair and vice chair were designated by the Stroke Council Manusc**t Oversight Committee. A writing committee roster was developed and approved by the Stroke Council with representatives from neurology, cardiology, radiology, surgery, nursing, pharmacy, and epidemiology/biostatistics. The writing group conducted a comprehensive review and synthesis of the relevant literature. The committee reviewed all compiled reports from computerized searches and conducted additional searches by hand. These searches are available on request. Searches were limited to English-language sources and human subjects. Literature citations were generally restricted to published manusc**ts appearing in journals listed in Index Medicus and reflected literature published as of August 1,2009. Because of the scope and importance of certain ongoing clinical trials and other emerging ***rmation, published abstracts were cited for ***rmational purposes when they were the only published ***rmation available, but recommendations were not based on abstracts alone. The references selected for this document are exclusively for peer-reviewed papers that are representative but not allinclusive, with priority given to references with higher levels of evidence. All members of the committee had frequent opportunities to review drafts of the document and reach a consensus with the final recommendations. Recommendations follow the American Heart Association (AHA) and the American College of Cardiology (ACC) methods of classifying the level of certainty of the treatment effect and the class of evidence

    本聲明旨在為臨床醫生提供在缺血性卒中或TIA患者中預防缺血性卒中的最新循證推薦。寫(xiě)作委員會(huì )主席和副主席由卒中委員會(huì )著(zhù)述監督委員會(huì ) (Stroke Council Manusc**t Oversight Committee)指定，其成員名單由卒中委員會(huì )擬定和批準，由來(lái)自神經(jīng)病學(xué)、心臟病學(xué)、放射學(xué)、外科學(xué)、護理學(xué)、藥劑學(xué)和流行病學(xué)／生物統計學(xué)等專(zhuān)業(yè) 的代表組成。寫(xiě)作組對相關(guān)文獻進(jìn)行了全面的回顧和綜合。委員會(huì )回顧了通過(guò)計算機檢索和進(jìn)一步的手工檢索獲得的所有匯編報告。如有需要，可提供這些檢索結 果。檢索限于以人為對象的英文文獻。文獻引文通常限于醫學(xué)索引(Index Medicus)列出的雜志于2009年8月1日之前發(fā)表的文獻。鑒于某些正在進(jìn)行的臨床試驗和其他新信息的重要性，如果摘要是唯一可獲得的公開(kāi)發(fā)表資 料，亦可出于情報目的予以引用，但不能單獨在摘要基礎上做出推薦。本文所選用的參考文獻均為經(jīng)過(guò)同行評議的具有代表性的論文，但并不包括全部文獻，而是優(yōu) 先選取具有更高證據水平草案，并就最終推薦達成共識。本指南的推薦意見(jiàn)遵循美國心臟協(xié)會(huì )和美國心血管病學(xué)學(xué)會(huì )關(guān)于療效確切性水平和證據等級的分類(lèi)方案。

    1.TIA和缺血性卒中亞型的定義

    2.所有TIA或缺血性卒中患者的危險因素控制

    3.大動(dòng)脈粥樣硬化患者的干預方法

    4.心源性栓塞的內科治療

    5.非心源性栓塞性卒中或TIA(特別是動(dòng)脈粥樣硬化性、腔隙性或原因不明性梗死)的抗栓治療

    6.其他特殊病因卒中患者的治療

    7.女性卒中

    8.顱內出血后抗凝治療的應用

    9 .實(shí)施指南的特殊方法以及指南在高危人群中的應用

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